Manuscripts – Press Release
Structural and Functional Versatility of the Amyloidogenic Non-Amidated Variant of the Anitmicrobial Peptide Citropin 1.3.
F. Strati, M. Pigozzi Cali, Y. Bloch, S. Mostafavi, J. Monistrol, A. Golubev, B. Rayan, E. Gustavsson, M. Landau. Biomacromolecules Epub ahead of print
Press:
Natural Antimicrobial Peptides Self-assemble as α/β Chameleon Amyloids.
P. Ragonis-Bachar*, B. Rayan*, E. Barnea, Y. Engelberg, A. Upcher, and M. Landau. Biomacromolecules Epub ahead of print
* Authors contributed equally.
Press:
The Cryo-EM Structures of two Amphibian Antimicrobial Cross-β Amyloid Fibrils.
R. Bücker, C. Seuring, C. Cazey, K. Veith, M. García-Alai, K. Grünewald, and M. Landau. Nature Communications 13: 4356; 2022.
Press:
- Twitter EMBL
- Twitter Robert Bücker
- CSSB News: Deciphering two antimicrobial amyloid structures using cryo-electron microscopy.
- University of Hamburg (in German): Entschlüsselung zweier antimikrobieller Amyloidstrukturen mittels Kryo-Elektronenmikroskopie
The amphibian antimicrobial peptide uperin 3.5 is a cross-α/cross-β chameleon functional amyloid.
Nir Salinas*, Einav Tayeb-Fligelman*, Massimo D. Sammito, Daniel Bloch, Raz Jelinek, Dror Noy, Isabel Usón, Meytal Landau. PNAS 118 (3) e2014442118; 2021 DOI: 10.1073/pnas.2014442118. *Authors contributed equally.
Press:
- Kan – Israel Public Broadcasting Corporation: Night News: “Research Assistant by Yuval Ofer” February 4, 2021
חדשות מבית כאן, תאגיד השידור הישראלי בפינת “עוזרת מחקר” ע”י יובל עופר
מה חדש באקדמיה בישראל? #חדשותהלילה עם המחקרים ששווה להכיר. בפינת הבכורה – הדור הבא של האנטיביוטיקה: עמידה, פועלת רק נגד מזהמים ומגיעה מקרפדה - Meytal in giving a radio Interview, February 2021 (in Hebrew) – “Three who know” Kan Tarbot (In Hebrew).
מיטל ב״שלושה שיודעים״, כאן תרבות - Article in Ynet: הקרפדה האוסטרלית והשריון הביולוגי שלה (article in Hebrew)
- Article in The Jerusalem Post: Tiny frogs create unique peptide to fight bacteria, study finds
- Article in Cosmos (Australia): Deadly weapon: frog peptide
- Article in Lavanguardia: La piel de un sapo australiano esconde una potente arma contra las bacterias (article in Spanish)
- Article in ECOticias.com: Sorpréndete con el sapo australiano (article in Spanish)
- Article in Agencia SINC: La piel de un sapo australiano esconde un arma mortal contra las bacterias (article in Spanish)
- Article in Yahoo Noticias: La piel de este sapo puede darnos nuevos antibióticos (article in Spanish)EMBL LinkedinEMBL FacebookEMBL Instagram
The Human LL-37(17-29) Antimicrobial Peptide Reveals a Functional Supramolecular Structure.
Y. Engelberg and M. Landau. Nat Commun 11, 3894 (2020) Full text
Press:
- Article in Ynet on Itzik’s Nat Comms paper פוענח המבנה האטומי של סיב פפטידי במערכת החיסון (article in Hebrew)
- Article in the Technion magazine on Itzik’s Nat Comms paper Page 24 – הגנה סיבית (article in Hebrew)
- Itzik in giving a radio Interview – “Three who know” Kan Tarbot (In Hebrew).
איציק ב״שלושה שיודעים״, כאן תרבות - Article in BIG NEWS NETWORK.COM on Itzik’s Nat Comms paper Israeli researchers decipher structure of vital component in immune system
- Article at the Technion Website on Itzik’s Nat Comms paper חוקרים בטכניון פענחו את המבנה האטומי של סיב פפטידי חשוב במערכת החיסון האנושית (article in Hebrew)
- Article in בריאות | בריאות | חוקרים בטכניון פענחו את המבנה האטומי של פפטיד אנטי-חיידקי חשוב במערכת החיסון (article in Hebrew)
- See Highlight in DESY Photon Science Annual Report 2020: Supramolecular structure of an antimicrobial peptide. Here see a link to full DESY Photon Science Annual Report 2020
- See article in ESRF Highlights 2020: Gorilla to the Rescue – Determining Novel Antimicrobial Fibril Structure. Here see a link to full ESRF Highlights 2020
Structural insight led to repurposing anti-Alzheimer’s compounds to fight bacterial biofilm
Perov*, O. Lidor*, N. Salinas*, N. Golan*, E. Tayeb-Fligelman, M. Deshmukh, D. Willbold, and M. Landau. PLoS Pathog 15(8):e1007978. Full text
Press:
- Technion: Inhibiting the Protective Mechanism of Bacteria
- An interview with Meytal in “Galey Zahal”, September 2019 (Hebrew)
- Technion: מדענים בטכניון הצליחו לפגוע במנגנון ההגנה של חיידקי סלמונלה בעזרת חומרים שפותחו במקור כנגד מחלת האלצהיימר
- An interview with Meytal in “Galey Zahal”, September 2019
A toxic bacterial peptide forms unique cross-α amyloid fibrils leading to killing human immune cells.
Tayeb-Fligelman, O. Tabachnikov, A. Moshe, O. Goldshimidt-Tran, M.R. Sawaya, N. Coquelle, J.-P. Colletier, M. Landau. Science 355(6327): 831-833; 2017 Full text
Press:
- The paper has been recommended by F1000
- ScienceNews: Bacteria’s amyloids display surprising structure
- Chemical & Engineering News (American Chemical Society magazine): Surprising amyloid structure solved
- Alzforum: Bizarre Twist on Amyloid Structure
- The European Peptide Society : Will the discovery of cross-α amyloid-like fibrils herald a new definition of amyloid?
- Ynet: החץ המורעל של החיידק הזהובThe Davidson Institute of Science Education, Weizmann Institute of Science
- Technion: החץ המורעל של החיידק הזהוב
- Technion: Novel Amyloid Structure Could Lead to New Types of Antibiotics
- Israel21c: New type of amyloid could lead to new antibiotics
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Photo Credit: Nitzan Zohar, Technion Spokesperson’s Office
